Fifth API Building

Fifth API Building

Fifth API Building

The Fifth API Building is currently Daito’s largest factory building dedicated to APIs.

Reaction vessel

Reaction vessel

Raw materials of substances to be synthesized are placed in reaction vessels and blended to cause chemical reaction and synthesize the mixture into the substances as an intended outcome. Temperature, time, and other conditions are strictly controlled.

Manhole in a reaction vessel

Manhole in a reaction vessel

Through this manhole, chemical reactions are observed from outside.

48-inch bottom-discharge centrifuge bowl

48-inch bottom-discharge centrifuge bowl

The inner part of a centrifuge bowl spins like the tub of a washing machine, separating the substances that have completed chemical reaction into the objective substances (solid) and solvent (liquid).

Horizontal centrifuge bowl for clean rooms

Horizontal centrifuge bowl for clean rooms

This type of centrifuge bowl is more effective in preventing impurities from mixing with substances in the bowl and more suitable to be installed in clean rooms than vertical centrifuge bowls.

Conical dryer <!-- -->

Conical dryer

From the wet crystals separated with the centrifuge bowl, organic solvent is volatilized, and the crystals are dried.
Decompression, heating, and rotation volatilize and suck up the organic solvent, which is then liquefied with a cooling device and recovered to prevent it from flowing out to the external environment.

Sixth API Building

Sixth API Building

Sixth API Building

The Sixth API Building was completed in November 2015.
This factory building is designed to be easily operable and suitable for high-mix low-volume production.

“One machine in one room”

“One machine in one room”

The Sixth API Building is designed based on the principle of “one machine in one room,” which has helped prevent the mixture of impurities and enabled the simultaneous manufacture of various products. The principle will also help further enhance the safety and quality of our products, as well as our productivity.

Gravity system <!-- -->

Gravity system

The gravity system enables us to make our manufacturing process more efficient, easier and more economical using gravitation.

Designed especially to be easily operable

Designed especially to be easily operable

All pieces of equipment are well designed from various aspects to prevent operational errors and to be easily operable. For example, the pipe layout in the entire building is unified.
Moreover, the installment of nitrogen purging equipment and static eliminators was planned early in the designing stage to ensure safety in a building where organic solvents would be handled.

A factory building that meets global standards

Meeting Japanese, U.S. and European standards

We are proud that the Sixth API Building meets Japanese, U.S. and European standards.
This building operates as a facility indispensable for us to stably provide world-class, high-quality and safe pharmaceutical products.

Shimo-okui Factory

On June 1, 2025, we absorbed our subsidiary, Daiwa Pharmaceutical Industry Co., Ltd., strengthening our high-quality, highly efficient production system.

Shimo-okui Factory

Shimo-okui Factory

We manufacture pharmaceutical active pharmaceutical ingredients and intermediates. We have a lineup ranging from small-scale 500-liter plants to mass-production plants of 5,000 liters, and many of our plants are multipurpose, providing efficient production.

Seventh API Building

With the establishment of the Seventh API Building in May 2022, the Daito Group endeavored to further reinforce its stable supply system and safety measures for APIs.

Seventh API Building

Seventh API Building

  • Investment amount: Approximately 3.9 billion yen
  • Production capacity: The new building will contribute to a 30% increase in production capacity of the Daito headquarters factory.
  • Completion: May 2022
  • Commercial production initiated in January 2023